MITOMAP A human mitochondrial genome database A compendium of polymorphisms and mutations in human mitochondrial DNA MITOMAP reports published data on human mitochondrial DNA variation. If you would like to add a paper and its data into MITOMAP, please email a pdf to mitomap@email.chop.edu. We appreciate your help.

2020 Update #1: On January 1, 2020 we added 48 new variants from 1040 new full-length (FL) and 1072 new control region (CR) GenBank sequences. This brings our total SNVs to 14431, the number of FL sequences to 50175, and the number of CR sequences to 73294. Our next sequence set update will be in May. See the GenBank Frequency Info page for details about our current sequence sets.

We have starred our user Favorites for seeking information on specific variants and for understanding the contents of our database.

MITOMAP Quick Reference & Tools

Allele Search - get point mutation data based on position

MITOMASTER - analyze any human mito SNV or nucleotide sequence

Tool Launchpad

The rCRS is GenBank number NC_012920.1. Click here for details.

General References		Illustrations:
The Annotated Human Mitochondrial DNA Sequence		View Figures
The rCRS & other mtDNAs..... GenBank Frequency Info		-Mitochondrial DNA Map
Amino Acid Translation Tables ...... MitoTIP tRNA Scoring		-Eleven pathological mutations in tRNA
Mitochondrial References, ALL ... • A-L only ... • M-Z only		-Mitochondrial energetics
Haplogroup Markers...... Most Common Variants		-Diabetes metabolism & the mitochondria
High Frequency Haplogroups....Mitobank		-World migrations
mtDNA Polypeptide Assignments		-mtDNA Trees
mtDNA Function Locations (Gene Loci)		Simple mtDNA Tree: Europe, Asia, Africa
Archived Reports:
... Mitochondrial Human Genome Report
... Common Continent-Specific mtDNA Variants, c.1995
... mtDNA RFLPs:... High Resolution... Low Resolution
General Variants (includes mini insertions & deletions)		Other databases & tools:
Control Region Variants (16024-576)		PhyloTree ... HaploGrep ... MSeqDR ... AmtDB
Coding & RNA Variants (577-16023, MTTF-MTTP)		HmtDB...PON tRNA... MitImpact... HmtVar
Somatic Mutations		MitoTool ... HvrBase++ ... GiiB-JST mtSNP ... mtDNA-Server
Collection of Submitted Variant Reports		EMPOP CR... Mitosearch... MitoMiner ... MitoWheel ...
Other Useful Mito Links on the Web		POLG Pathogenicity Server ...POLG @NIEHS ... MitoBreak... MitoAge
		Mamit-tRNA/mitotRNAdb... MitoFit... Aminoacyl tRNA Synthetases
Disease Mutations (reports of possible disease-associations)
Organized by mtDNA location:
rRNA/tRNA Mutations, all       View Cfrm status only
Coding & Non-Coding/Control Region Mutations, all       View Cfrm status only
Organized by phenotype:
rRNA/tRNA Mutations
Coding & Control Region Mutations
LHON Mutations
Major Rearrangements
MtDNA Deletions
Multiple mtDNA Deletions Within Individuals
MtDNA Inversions
MtDNA Simple Insertions
MtDNA Complex Rearrangements
Nuclear Genes Involved in Mitochondrial Disease
Structural Nuclear Genes in Mitochondrial Disease
Non-Structural Nuclear Genes in Mitochondrial Disease
Mitochondrial Pseudogenes
How to Cite MITOMAP & Submit Publications
How to cite MITOMAP & Terms of Use
Submitting articles: If you would like to submit published articles to be included in mitomap, please send the citation & a pdf to mitomap@email.chop.edu. (please put the word "Mitomap" in the subject line)
Support and Advocacy
United Mitochondrial Disease Foundation		Miracles for Mito
About Mitochondrial Disease - Mitoaction's FAQ		Audio Podcasts on iTunes- Mitoaction
Foundation for Mitochondrial Medicine		Mitochondrial Research Guild
Mito Hope and Help		MitoCanada
Other
The Human Family Tree:10 Adams and 18 Eves		Mitochondria Interest Group Video Casts

Map of the Human Mitochondrial DNA

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~ Celebrating 24 years! ~
Mitomap has been continuously updated since 1996.